BioCryst Pharmaceuticals - PharmaKB

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Company ReportsBioCryst Pharmaceuticals

BioCryst Pharmaceuticals(BCRX)

BioCryst Pharmaceuticals, Inc. is an American pharmaceutical company headquartered in Durham, North Carolina. The company is a late stage biotech company that focuses on oral drugs for rare and serious diseases. BioCryst's antiviral drug peramivir (Rapivab) was approved by FDA in December 2014. It has also been approved in Japan, Korea, and China.

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Financial

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Alpivab	Peramivir	2018-04-13	2027	Human influenza
Orladeyo	Berotralstat	2020-12-03	2035-2039	Hereditary angioedemas
Rapivab	Peramivir	2014-12-19	2027	Human influenza

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

hereditary angioedemas

,

,

antibiotic prophylaxis

human influenza

,

,

,

,

nasal obstruction

,

,

,

,

renal insufficiency

,

,

,

,

marburg virus disease

,

ebola hemorrhagic fever

,

,

communicable diseases

,

filoviridae infections

hereditary angioedemas

,

healthy volunteers/patients

,

renal insufficiency

,

pharmacokinetics

,

biological availability

,

,

,

,

chronic kidney failure

,

kidney diseases

,

therapeutic equivalency

,

cardiovascular diseases

,

bariatric surgery

,

thromboembolism

,

venous thromboembolism

,

,

acute coronary syndrome

,

,

,

myocardial infarction

,

myocardial ischemia

,

,

,

transcatheter aortic valve replacement

,

,

percutaneous coronary intervention

,

unstable angina

,

knee osteoarthritis

,

hip osteoarthritis

,

,

,

,

coronavirus infections

,

,

respiratory insufficiency

,

communicable diseases

,

rheumatic diseases

,

collagen diseases

,

coronary disease

,

,

intracranial arteriosclerosis

,

arteriosclerosis

,

atrial fibrillation

,

,

,

venous thrombosis

,

pulmonary embolism

,

coronary artery disease

,

peripheral arterial disease

,

,

peripheral vascular diseases

,

,

disease progression

,

,

,

replacement arthroplasty knee

,

replacement arthroplasty hip

,

congenital heart defects

,

,

fontan procedure

Sodium chloride

,

,

,

,

,

,

depressive disorder

,

,

streptococcal infections

,

streptococcus agalactiae

,

,

acute kidney injury

,

wounds and injuries

,

,

,

aplastic anemia

,

,

hematologic neoplasms

,

,

cutaneous malignant melanoma

,

major depressive disorder

,

suicidal ideation

,

stomach neoplasms

,

bacterial infections

,

gram-positive bacterial infections

,

diabetic nephropathies

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

,

parkinson disease

,

healthy volunteers/patients

,

peritoneal neoplasms

,

intestinal obstruction

,

triple negative breast neoplasms

,

complex regional pain syndromes

,

reflex sympathetic dystrophy

,

somatoform disorders

,

,

,

congenital hyperinsulinism

,

nesidioblastosis

,

hyperinsulinism

,

,

eosinophilic esophagitis

,

,

sickle cell anemia

,

treatment-resistant depressive disorder

,

meningococcal infections

,

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

,

,

non-small-cell lung carcinoma

,

,

homozygous familial hypercholesterolemia

,

,

meningococcal meningitis

,

cardiovascular diseases

,

,

kidney diseases

,

renal cell carcinoma

,

,

cystic fibrosis

,

prostatic neoplasms

,

,

,

pancreatic neoplasms

,

chronic renal insufficiency

,

kidney transplantation

,

graft rejection

,

,

,

,

,

japanese encephalitis

,

respiratory tract infections

,

,

,

metabolic bone diseases

,

,

,

pulmonary eosinophilia

,

hepatocellular carcinoma

,

liver neoplasms

,

gastrointestinal stromal tumors

,

atherosclerosis

,

,

,

diabetes complications

,

vitreous hemorrhage

,

,

essential hypertension

,

metabolic syndrome

,

,

,

systolic murmurs

,

isolated systolic hypertension

,

neoplasm metastasis

,

,

human influenza

,

diabetes mellitus

,

multiple myeloma

,

plasma cell neoplasms

,

breast neoplasms

,

hypersensitivity

,

left ventricular hypertrophy

,

,

,

,

communicable diseases

,

,

diabetic retinopathy

,

,

insulin resistance

,

prehypertension

,

staphylococcal skin infections

,

infectious skin diseases

,

bacterial skin diseases

,

,

,

type 2 diabetes mellitus

,

,

,

retinal diseases

,

hip osteoarthritis

,

,

food hypersensitivity

,

abdominal obesity

,

retinal neovascularization

,

pathologic neovascularization

,

migraine disorders

,

migraine without aura

,

angina pectoris

,

microvascular angina

,

,

migraine with aura

,

health risk behaviors

,

vascular stiffness

hyperlipidemias

,

gastrointestinal stromal tumors

,

,

iron-deficiency anemia

,

iron deficiencies

,

,

,

,

small cell lung carcinoma

,

healthy volunteers/patients

,

,

primary myelofibrosis

,

myeloid leukemia acute

,

myeloid leukemia

,

,

hepatocellular carcinoma

,

,

plexiform neurofibroma

,

neurofibromatoses

,

,

,

,

chronic obstructive pulmonary disease

,

,

triple negative breast neoplasms

,

,

,

essential thrombocythemia

,

polycythemia vera

,

,

,

lupus nephritis

,

,

inflammatory breast neoplasms

,

prostatic neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

wiskott-aldrich syndrome

,

bcr-abl positive chronic myelogenous leukemia

,

,

,

hyperlipoproteinemia type ii

,

organ transplantation

,

homozygous familial hypercholesterolemia

,

cryopyrin-associated periodic syndromes

,

myelodysplastic syndromes

,

,

liver transplantation

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

parkinson disease

,

,

,

juvenile arthritis

,

,

,

,

hepatitis b virus

,

,

,

,

vision disorders

,

,

pituitary acth hypersecretion

,

acth-secreting pituitary adenoma

,

,

acute coronary syndrome

,

,

,

pulmonary eosinophilia

,

pancreatic neoplasms

,

,

,

kidney transplantation

,

,

hypercholesterolemia

,

cardiovascular diseases

,

atherosclerosis

,

chronic kidney failure

,

kidney diseases

,

thrombocytopenia

,

,

breast neoplasms

,

,

renal insufficiency

,

,

,

,

chronic renal insufficiency

,

,

renal replacement therapy

,

drug-related side effects and adverse reactions

,

heart transplantation

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

,

cystic fibrosis

,

pseudomonas infections

,

type 2 diabetes mellitus

,

diabetes mellitus

,

multiple myeloma

,

plasma cell neoplasms

,

transplantation

,

cytomegalovirus infections

,

communicable diseases

,

,

,

,

lymphoid leukemia

,

,

t-cell lymphoma

,

t-cell lymphoma cutaneous

,

b-cell chronic lymphocytic leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

t-cell lymphoma peripheral

,

t-cell leukemia

,

,

,

,

renal insufficiency

paroxysmal hemoglobinuria

,

,

kidney diseases

,

glomerulonephritis

,

iga glomerulonephritis

,

membranous glomerulonephritis

,

,

,

falciparum malaria

,

breast neoplasms

,

ebola hemorrhagic fever

,

,

klebsiella infections

,

pulmonary arterial hypertension

,

cardiovascular diseases

,

,

pulmonary hypertension

influenza in birds

,

,

multiple sclerosis

,

,

,

,

,

orthomyxoviridae

,

,

communicable diseases

,

infectious myxomatosis

,

h1n1 subtype influenza a virus

,

,

,

,

,

viral hemorrhagic fevers

,

,

,

,

,

,

,

meningococcal infections

,

,

haemophilus influenzae type b

,

inactivated vaccines

,

,

human influenza

,

orthomyxoviridae infections

,

healthy volunteers/patients

,

,

,

myocardial infarction

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

,

,

immune system diseases

,

pregnancy complications

,

,

toxicological phenomena

,

,

respiratory syncytial virus infections

,

,

,

,

atrial fibrillation

,

cardiovascular diseases

,

coronary disease

,

cardiac arrhythmias

,

,

,

diabetes mellitus

,

respiratory tract infections

,

inferior wall myocardial infarction

,

severe acute respiratory syndrome

,

behavior and behavior mechanisms

,

hereditary angioedemas

,

1

2

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